| |
|
|
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha : |
29/01/2020 |
|
Actualizado : |
29/01/2020 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Autor : |
CARVALHO, F.E.; ESPIGOLAN, R.; BERTON, M.P.; NETO, J.B.S.; SILVA, R.P.; GRIGOLETTO, L.; SILVA, R.M.O.; FERRAZ, J.B.S.; ELER, J.P.; AGUILAR, I.; LÔBO, R.B.; BALDI, F. |
|
Afiliación : |
F.E.CARVALHO, Departament of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), Pirassununga/SP, Brazil; R. ESPIGOLAN, Departament of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), Pirassununga/SP, Brazil; M. P. BERTON, Departament of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Jaboticabal/SP, Brazil; J. B. S. NETO, Departament of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Jaboticabal/SP, Brazil; R. P. SILVA, Departament of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), Pirassununga/SP, Brazil; L. GRIGOLETTO, Departament of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), Pirassununga/SP, Brazil; R. M. O. SILVA, Zoetis, 1240 Dr. Chucri Zaidan Street, Edifício Morumbi Corporate, Diamond Tower, 4th floor, São Paulo, SP, Brazil; J. B. S. FERRAZ, Departament of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), Pirassununga/SP, Brazil; J. P . ELER, Departament of Veterinary Medicine, College of Animal Science and Food Engineer, University of São Paulo (USP), Pirassununga/SP, Brazil; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; LÔBO, R.B., Nacional Association of Breeders and Researchers (ANCP), Ribeirão Preto, SP, Brazil; F. BALDI, Departament of Animal Science, College of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Jaboticabal/SP, Brazil. |
|
Título : |
Genome-wide association study and predictive ability for growth traits in Nellore cattle. |
|
Fecha de publicación : |
2020 |
|
Fuente / Imprenta : |
Livestock Science, January 2020, Volume 231, Article number 103861. OPEN ACCESS. Doi: https://doi.org/10.1016/j.livsci.2019.103861 |
|
ISSN : |
1871-1413 |
|
DOI : |
10.1016/j.livsci.2019.103861 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received 25 June 2019 / Revised 29 October 2019 / Accepted 4 November 2019 / Available online 6 November 2019.
Funding information: F.E. CARVALHO received a scholarship from Coordinating for the Improvement of Higher Education Personnel (CAPES) in conjunction with the Postgraduate Program on Zootecnia, Universidade de São Paulo, Faculdade de Zootecnia e Engenharia de Alimentos (FZEA, USP). To National Association of Breeders and Researchers (ANCP, Ribeirão Preto-SP, Brazil). To Fapesp, ( Sao Paulo Research Foundation , grants #2016/222751-6 #2017/10493-5 ). F.B held productivity research fellowships from The Brazilian National Council for Scientific and Technological Development (CNPQ). |
|
Contenido : |
ABSTRACT.
This study aimed to identify genomic regions influencing growth traits in Nellore cattle and evaluate the predictive ability of each trait based on results obtained from single-step genome-wide association analyzes (ssGWAS) considering different single nucleotide polymorphims (SNP) densities of markers. The National Association of Breeders and Researchers provided the dataset, from eighteen Nellore herds participating of the Nellore Brazilian breeding program. The traits birth weight (BW), adjusted weight at 210 (W210) and at 450 (W450) days of age and adult cow weight (ACW) were considered. A total of 963 animals, genotyped using the Illumina BovineHD BeadChip, were used as a reference population to impute genotypes of 7,689 animals, genotyped in low-density panel. Genotype imputation was performed using the FImpute 2.2 software. The ssGWAS was used to identify genomic regions associated to growth traits. Several genes in enrichment analysis were related to muscle and adipose tissue development and metabolism, feed efficiency, milk composition and maternal behavior. The predictive ability varied from low (0.10) to moderate (0.68). The predictive ability and bias for both panels were similar for all traits. The results found in this study should improve the understanding of genetic and physiologic mechanism associated with growth traits. However, the association of these results with other approaches, like system biologic and other omics information should improve the identification of causative genetic variants in growth traits in indicine cattle.
© 2019 Elsevier B.V. MenosABSTRACT.
This study aimed to identify genomic regions influencing growth traits in Nellore cattle and evaluate the predictive ability of each trait based on results obtained from single-step genome-wide association analyzes (ssGWAS) considering different single nucleotide polymorphims (SNP) densities of markers. The National Association of Breeders and Researchers provided the dataset, from eighteen Nellore herds participating of the Nellore Brazilian breeding program. The traits birth weight (BW), adjusted weight at 210 (W210) and at 450 (W450) days of age and adult cow weight (ACW) were considered. A total of 963 animals, genotyped using the Illumina BovineHD BeadChip, were used as a reference population to impute genotypes of 7,689 animals, genotyped in low-density panel. Genotype imputation was performed using the FImpute 2.2 software. The ssGWAS was used to identify genomic regions associated to growth traits. Several genes in enrichment analysis were related to muscle and adipose tissue development and metabolism, feed efficiency, milk composition and maternal behavior. The predictive ability varied from low (0.10) to moderate (0.68). The predictive ability and bias for both panels were similar for all traits. The results found in this study should improve the understanding of genetic and physiologic mechanism associated with growth traits. However, the association of these results with other approaches, like system biologic and other omics information should improve ... Presentar Todo |
|
Palabras claves : |
BEEF CATTLE; Genomic; Predictive ability; Single nucleotide polymosphism. |
|
Asunto categoría : |
L10 Genética y mejoramiento animal |
|
URL : |
https://www.sciencedirect.com/science/article/pii/S1871141319308935/pdfft?md5=2a644d20a870893fa10662e7fb7ecf40&pid=1-s2.0-S1871141319308935-main.pdf
|
|
Marc : |
LEADER 03332naa a2200337 a 4500
001 1060718
005 2020-01-29
008 2020 bl uuuu u00u1 u #d
022 $a1871-1413
024 7 $a10.1016/j.livsci.2019.103861$2DOI
100 1 $aCARVALHO, F.E.
245 $aGenome-wide association study and predictive ability for growth traits in Nellore cattle.$h[electronic resource]
260 $c2020
500 $aArticle history: Received 25 June 2019 / Revised 29 October 2019 / Accepted 4 November 2019 / Available online 6 November 2019. Funding information: F.E. CARVALHO received a scholarship from Coordinating for the Improvement of Higher Education Personnel (CAPES) in conjunction with the Postgraduate Program on Zootecnia, Universidade de São Paulo, Faculdade de Zootecnia e Engenharia de Alimentos (FZEA, USP). To National Association of Breeders and Researchers (ANCP, Ribeirão Preto-SP, Brazil). To Fapesp, ( Sao Paulo Research Foundation , grants #2016/222751-6 #2017/10493-5 ). F.B held productivity research fellowships from The Brazilian National Council for Scientific and Technological Development (CNPQ).
520 $aABSTRACT. This study aimed to identify genomic regions influencing growth traits in Nellore cattle and evaluate the predictive ability of each trait based on results obtained from single-step genome-wide association analyzes (ssGWAS) considering different single nucleotide polymorphims (SNP) densities of markers. The National Association of Breeders and Researchers provided the dataset, from eighteen Nellore herds participating of the Nellore Brazilian breeding program. The traits birth weight (BW), adjusted weight at 210 (W210) and at 450 (W450) days of age and adult cow weight (ACW) were considered. A total of 963 animals, genotyped using the Illumina BovineHD BeadChip, were used as a reference population to impute genotypes of 7,689 animals, genotyped in low-density panel. Genotype imputation was performed using the FImpute 2.2 software. The ssGWAS was used to identify genomic regions associated to growth traits. Several genes in enrichment analysis were related to muscle and adipose tissue development and metabolism, feed efficiency, milk composition and maternal behavior. The predictive ability varied from low (0.10) to moderate (0.68). The predictive ability and bias for both panels were similar for all traits. The results found in this study should improve the understanding of genetic and physiologic mechanism associated with growth traits. However, the association of these results with other approaches, like system biologic and other omics information should improve the identification of causative genetic variants in growth traits in indicine cattle. © 2019 Elsevier B.V.
653 $aBEEF CATTLE
653 $aGenomic
653 $aPredictive ability
653 $aSingle nucleotide polymosphism
700 1 $aESPIGOLAN, R.
700 1 $aBERTON, M.P.
700 1 $aNETO, J.B.S.
700 1 $aSILVA, R.P.
700 1 $aGRIGOLETTO, L.
700 1 $aSILVA, R.M.O.
700 1 $aFERRAZ, J.B.S.
700 1 $aELER, J.P.
700 1 $aAGUILAR, I.
700 1 $aLÔBO, R.B.
700 1 $aBALDI, F.
773 $tLivestock Science, January 2020, Volume 231, Article number 103861. OPEN ACCESS. Doi: https://doi.org/10.1016/j.livsci.2019.103861
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
|
 | Acceso al texto completo restringido a Biblioteca INIA Tacuarembó. Por información adicional contacte bibliotb@tb.inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA Tacuarembó. |
|
Fecha actual : |
21/02/2014 |
|
Actualizado : |
31/10/2019 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
SCARAMUZZI, R.J.; BAIRD, D.T.; CAMPBELL, B.K.; DRIANCOURT, M.A.; DUPONT, J.; FORTUNE, J.E.; GILCHRIST, R.B.; MARTIN, G.B.; MCNATTY, K.P.; MCNEILLY, A.S.; MONGET, P.; MONNIAUX, D.; VIÑOLES, C.; WEBB, R. |
|
Afiliación : |
R.J. SCARABUZZI, INRA, UMR85 Physiologie de la Reproduction et des Comportements, Centre INRA de Tours, 37380 Nouzilly, France.B Department of Veterinary Basic Sciences, The Royal Veterinary College, Hawkshead Lane, North Mimms, Hertfordshire AL9 7TA, UK; D.T. BAIRD, University of Edinburgh, Centre for Reproductive Biology, The Queen?s Medical; B.K. CAMPBELL, University of Nottingham, Division of Obstetrics and Gynaecology, The Queen?s Medical Centre, Nottingham NG7 2UH, UK.; M.A. DRIANCOURT, Intervet Schering Plough Animal Health, Intervet Pharma R & D, BP 67131, 49071 Beaucouze´, France; J. DUPONT, INRA, UMR85 Physiologie de la Reproduction et des Comportements, Centre INRA de Tours, 37380 Nouzilly, France.; J.E. FORTUNE, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.; R.B. GILCHRIST, Robinson Institute, School of Paediatrics and Reproductive Health, Medical School South, University of Adelaide, SA 5005, Australia; G.B. MARTIN, Animal Production Systems, UWA Institute of Agriculture, The University of Western Australia, Crawley, WA 6009, Australia; K.P. MCNATTY, School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.; A.S. MCNEILLY, School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.; P. MONGET, INRA, UMR85 Physiologie de la Reproduction et des Comportements, Centre INRA de Tours, 37380 Nouzilly, France.; D. MONNIAUX, INRA, UMR85 Physiologie de la Reproduction et des Comportements, Centre INRA de Tours, 37380 Nouzilly, France.; CAROLINA VIÑOLES GIL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; R. WEBB, L University of Nottingham, Division of Animal Science, School of Biosciences, Loughborough, Leicestershire LE12 5RD, UK. |
|
Título : |
Regulation of folliculogenesis and the determination of ovulation rate in ruminants (Review). |
|
Fecha de publicación : |
2011 |
|
Fuente / Imprenta : |
Reproduction, Fertility and Development, 2011, Volume 23, Issue 3, Pages 444-467. |
|
DOI : |
10.1071/RD09161 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Manuscript received 11 July 2009 // Accepted 5 October 2010. |
|
Contenido : |
The paper presents an update of our 1993 model of ovarian follicular development in ruminants, based on knowledge gained from the past 15 years of research. The model addresses the sequence of events from follicular formation in fetal life, through the successive waves of follicular growth and atresia, culminating with the emergence of ovulatory follicles during reproductive cycles. The original concept of five developmental classes of follicles, defined primarily by their responses to gonadotrophins, is retained: primordial, committed, gonadotrophin-responsive, gonadotrophin-dependent and ovulatory follicles. The updated model has more extensive integration of the morphological, molecular and cellular events during folliculogenesis with systemic events in the whole animal. It also incorporates knowledge on factors that influence oocyte quality and the critical roles of the oocyte in regulating follicular development and ovulation rate. The original hypothetical mechanisms determining ovulation rate are retained but with some refinements; the enhanced viability of gonadotrophin-dependent follicles and increases in the number of gonadotrophinresponsive follicles by increases in the throughput of follicles to this stage of growth. Finally, we reexamine how these two mechanisms, which are thought not to be mutually exclusive, appear to account for most of the known genetic and environmental effects on ovulation rate |
|
Palabras claves : |
EWE; FOLLICLE; NUTRITION; OOCYTE; OVARY. |
|
Thesagro : |
PRODUCCION ANIMAL. |
|
Asunto categoría : |
L53 Fisiología Animal - Reproducción |
|
Marc : |
LEADER 02522naa a2200373 a 4500
001 1017988
005 2019-10-31
008 2011 bl uuuu u00u1 u #d
024 7 $a10.1071/RD09161$2DOI
100 1 $aSCARAMUZZI, R.J.
245 $aRegulation of folliculogenesis and the determination of ovulation rate in ruminants (Review).$h[electronic resource]
260 $c2011
500 $aArticle history: Manuscript received 11 July 2009 // Accepted 5 October 2010.
520 $aThe paper presents an update of our 1993 model of ovarian follicular development in ruminants, based on knowledge gained from the past 15 years of research. The model addresses the sequence of events from follicular formation in fetal life, through the successive waves of follicular growth and atresia, culminating with the emergence of ovulatory follicles during reproductive cycles. The original concept of five developmental classes of follicles, defined primarily by their responses to gonadotrophins, is retained: primordial, committed, gonadotrophin-responsive, gonadotrophin-dependent and ovulatory follicles. The updated model has more extensive integration of the morphological, molecular and cellular events during folliculogenesis with systemic events in the whole animal. It also incorporates knowledge on factors that influence oocyte quality and the critical roles of the oocyte in regulating follicular development and ovulation rate. The original hypothetical mechanisms determining ovulation rate are retained but with some refinements; the enhanced viability of gonadotrophin-dependent follicles and increases in the number of gonadotrophinresponsive follicles by increases in the throughput of follicles to this stage of growth. Finally, we reexamine how these two mechanisms, which are thought not to be mutually exclusive, appear to account for most of the known genetic and environmental effects on ovulation rate
650 $aPRODUCCION ANIMAL
653 $aEWE
653 $aFOLLICLE
653 $aNUTRITION
653 $aOOCYTE
653 $aOVARY
700 1 $aBAIRD, D.T.
700 1 $aCAMPBELL, B.K.
700 1 $aDRIANCOURT, M.A.
700 1 $aDUPONT, J.
700 1 $aFORTUNE, J.E.
700 1 $aGILCHRIST, R.B.
700 1 $aMARTIN, G.B.
700 1 $aMCNATTY, K.P.
700 1 $aMCNEILLY, A.S.
700 1 $aMONGET, P.
700 1 $aMONNIAUX, D.
700 1 $aVIÑOLES, C.
700 1 $aWEBB, R.
773 $tReproduction, Fertility and Development, 2011, Volume 23, Issue 3, Pages 444-467.
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Tacuarembó (TBO) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
